The microecological balance of the lung and intestine plays an important role in preventing infection,regulating immunity,regulating metabolism,and so on.This paper discusses the relationship between lung and intestine and the importance of microecological balance of lung and intestine from the research of traditional Chinese medicine and modern medicine,and finds that the microecological imbalance of intestinal microflora is one of the mechanisms of respiratory infection.It has also been further demonstrated that the spleen-strengthening Formula in traditional Chinese medicine can increase intestinal probiotics,reduce pathogenic bacteria,reduce endotoxins and inflammatory mediators released by pathogenic bacteria,play a role in enhancing the immune protection of the intestinal mucosal barrier and reducing antibiotic resistance,thereby reducing respiratory infections and increasing clinical curative effect.The spleen-invigorating Formula that can regulate the intestinal microecology will become a new entry point for the clinical treatment of respiratory tract infections,and provide new ideas for the clinical treatment of respiratory tract infections.