Fibrosis refers to the increase of fibrous connective tissue and decrease of parenchymal cells in organ tissues,which occur in lungs,heart,liver,kidney,skin and other organs and tissues.Continuous progressive fibrosis can lead to structural damage and functional decline,or even functional failure.Studies show that autophagy is related to the occurrence,development and outcome of fibrotic diseases.The therapeutic effect of Traditional Chinese medicine(TCM) on fibrotic diseases is definite,and its mechanism is related to autophagy or pathway.The paper reviewed the treatment of fibrosis by autophagy with TCM,in order to exploring the new direction of TCM in the treatment of fibrotic diseases.