To explore the research progress of TCM syndrome differentiation and treatment of acute ischemic stroke.Through the analysis of relevant literatures on the treatment of acute ischemic stroke by TCM syndrome differentiation and treatment in recent years,the progress of TCM treatment in the acute stage of ischemic stroke was explained from the etiology and pathogenesis to syndrome differentiation and treatment.The treatment of syndrome differentiation in acute stage of ischemic stroke is widely used in clinic,and the combination of traditional Chinese and western medicine can improve clinical efficacy.The treatment of TCM syndrome differentiation in the acute stage of ischemic stroke has advantages of improving clinical efficacy and reducing adverse reactions,but lacks objective and unified criteria for syndrome differentiation.