| 引用本文:吴焕淦1,2,朱璐1,刘慧荣1,2,马晓芃1,2,刘世敏3,赵琛3,余曙光4,常小荣5,胡玲6,王照钦2,彭广彬1,李国娜3,吴璐一1,2.灸法治疗胃肠疾病的效应机制研究[J].世界中医药,2022,(03):. |
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| 灸法治疗胃肠疾病的效应机制研究 |
| Mechanism of Moxibustion in the Treatment of Gastrointestinal Diseases |
| 投稿时间：2022-01-06 |
| DOI：10.3969/j.issn.1673-7202.2022.03.001 |
| 中文关键词: 灸法 胃肠疾病 机制 黏膜 |
| English Keywords:Moxibustion Gastrointestinal diseases Mechanism Mucosa |
| 基金项目:国家自然科学基金面上项目（81774405，81973953，82174501）；国家中医药领军人才支持计划“岐黄学者” |
| 作者 | 单位 | | 吴焕淦1,2,朱璐1,刘慧荣1,2,马晓芃1,2,刘世敏3,赵琛3,余曙光4,常小荣5,胡玲6,王照钦2,彭广彬1,李国娜3,吴璐一1,2 | 1 上海中医药大学附属岳阳中西医结合医院，上海，200437； 2 上海市针灸经络研究所，上海，200030； 3 上海中医药大学针灸推拿学院，上海，201203； 4 成都中医药大学，成都，610075； 5 湖南中医药大学，长沙，410208； 6 安徽中医药大学，合肥，230012 |
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| 中文摘要: |
| 21世纪以来，国内外灸法治疗胃肠疾病的理论、临床及实验研究热度攀升，科技部2次立项的国家“973计划”灸法项目阐明了多项灸法关键科学问题，实现了灸法研究重大创新，推动灸法治疗胃肠疾病的临床实践，并在基础研究领域取得了丰硕的研究成果。现简述灸法治疗胃肠疾病的研究概况，并总结出灸法治疗胃肠疾病的效应机制研究主要围绕慢性萎缩性胃炎、胃溃疡、功能性胃肠病、炎症性肠病（溃疡性结肠炎、克罗恩病）、消化道肿瘤而展开，表现为多因子、多靶点、多通路的作用特点，具体效应机制归纳为调节胃肠运动、缓解内脏痛、修复和保护胃肠黏膜、调节肠道菌群、改善消化道肿瘤术后并发症及化疗不良反应5个方面。研究表明，灸法治疗胃肠疾病优势明确，相关基础研究值得进一步深入探索。 |
| English Summary: |
| Since the new century，the theoretical，clinical，and experimental research on moxibustion in the treatment of gastrointestinal diseases in China and abroad has increased.Two projects of the National Basic Research Program (973 Program) in moxibustion initiated by the Ministry of Science and Technology of China have clarified several key scientific problems of moxibustion，realized major innovation in moxibustion research，promoted the clinical practice of moxibustion in the treatment of gastrointestinal diseases，and achieved fruitful results in the basic research.This study briefly introduced the research overview and mechanism of moxibustion in the treatment of gastrointestinal diseases，including chronic atrophic gastritis，gastric ulcer，functional gastrointestinal diseases，inflammatory bowel diseases (e.g.，ulcerative colitis and Crohn's disease)，and gastrointestinal tumors，which is characterized by multi-factor，multi-target，and multi-pathway effects.The therapeutic effect was achieved by regulating gastrointestinal movement，alleviating visceral pain，repairing and protecting gastrointestinal mucosa，regulating intestinal flora，and improving postoperative complications of gastrointestinal tumors and adverse events of chemotherapy，which could be summarized as its specific mechanism.Existing studies have shown that moxibustion has definite therapeutic efficacy on gastrointestinal diseases，and the relevant basic research is worthy of further implementation. |
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