Traditional Chinese medicine(TCM) has some curative effect for senile dementia.However，based on the existing pathogenesis-related theories of senile dementia，it is difficult to improve the clinical efficacy.Therefore，it is necessary to interpret its pathogenesis from a new perspective.This paper uses a new perspective of Xuanfu theory to interpret the pathogenesis of senile dementia，and proposes that Xuanfu depression in the brain is one of the key pathogenesis of senile dementia.The corresponding treatment method is to open Xuanfu.A total of 3 types of medicines，pungent dissolving drugs，resuscitation with aromatic drugs and insect drugs，have achieved the purpose of opening Xuanfu.Based on the existing treatment of senile dementia，it is expected to improve the clinical efficacy in combination with the opening of Xuanfu method.