益气活血方治疗不稳定型心绞痛介入术后回顾性分析
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国家自然科学基金项目(81573900);北京市科学技术委员会——首都临床特色应用研究专项资助课题(Z181100001718064);中央高校基本科研业务费专项资金资助项目(2019-JYB-XS-215)


Retrospective Analysis of Yiqi Huoxue Recipe in the Treatment of Patients with Unstable Angina Pectoris Undergoing Percutaneous Coronary Intervention
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    摘要:

    目的:探讨益气活血方治疗不稳定型心绞痛(气虚血瘀型)经皮冠状动脉介入治疗(PCI)术后患者的临床疗效及应用价值。方法:选取2017年9月1日至2019年12月31日北京中医药大学第二临床医学院收治的西医诊断为不稳定型心绞痛并行PCI,中医诊断为胸痹心痛病(气虚血瘀型)的患者98例作为研究对象进行回顾性研究,通过查阅病历并进行电话随访,按照是否服用益气活血方分为对照组(n=54)和观察组(n=44),对2组患者基本临床资料(一般资料,中医症状积分,不稳定型心绞痛疗效,心电图疗效,6个月再住院率)进行统计分析。结果:益气活血方观察组与对照组比较,在中医证候积分疗效方面差异有统计学意义(P<0.05),治疗后各项中医症状积分比较,其中胸痛、心悸、自汗,观察组明显低于对照组,差异有统计学意义(均P<0.05)。结论:益气活血方可以明显改善患者的中医证候,尤其是在胸痛、心悸、自汗这3个方面改善最为明显。

    Abstract:

    To explore the clinical efficacy and application value of Yiqi Huoxue Recipe in the treatment of patients with unstable angina pectoris(qi deficiency and blood stasis type) undergoing percutaneous coronary intervention(PCI).Methods:There were 98 patients selected for retrospective study who were diagnosed with unstable angina pectoris undergoing PCI by western medicine and chest impediment and heart pain(qi deficiency and blood stasis type) by traditional Chinese medicine(TCM) in the Second Clinical Medical College of Beijing University of Chinese medicine from September 1,2017 to December 31,2019.By consultation of the medical records and telephone follow-up,the patients were divided into control group(n=54) and observation group(n=44) in the presence and absence of taking Yiqi Huoxue Recipe.The basic clinical data(general information,TCM symptom score,curative effect of unstable angina pectoris,electrocardiogram(ECG) change and re-hospitalization rate in half a year) of the two groups were statistically analyzed.Results:There was difference in the improvement of TCM syndrome score between observation group and control group(P<0.05).After treatment,various TCM symptom scores were compared,and the observation group had lower scores in chest pain,palpitation and spontaneous sweating than the control group(P<0.05).Conclusion:Yiqi Huoxue Recipe can significantly improve the TCM syndrome of patients,especially in chest pain,palpitation and spontaneous sweating.

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李拯宇,吴旸,崔杰,逯金金,李星星,范宗静.益气活血方治疗不稳定型心绞痛介入术后回顾性分析[J].世界中医药,2022,(05).

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  • 收稿日期:2020-06-16
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  • 在线发布日期: 2022-05-15
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