| 引用本文:李芷悦1，李宗芳2，任培中1，陈秋仪1，崔红生1.痰热清注射液治疗肺部耐药菌感染疗效及安全性的系统评价[J].世界中医药,2022,(07):. |
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| 痰热清注射液治疗肺部耐药菌感染疗效及安全性的系统评价 |
| Meta-analysis of Efficacy and Safety of Tanreqing Injection in the Treatment of Drug-resistant Pulmonary Infection |
| 投稿时间：2020-03-13 |
| DOI：10.3969/j.issn.1673-7202.2022.07.017 |
| 中文关键词: 痰热清注射液 耐药菌肺部感染 Meta分析 随机对照试验 系统评价 临床疗效 鲍曼不动杆菌 铜绿假单胞菌 金黄色葡萄球菌 |
| English Keywords:Tanreqing Injection Drug-resistant pulmonary infection Meta-analysis Randomized controlled trial Systematic review Clinical efficacy Acinetobacter baumannii Pseudomonas aeruginosa Staphylococcus aureus |
| 基金项目:山东省中医药科技发展计划项目(2019-0803) |
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| 中文摘要: |
| 目的:评价痰热清注射液联合西药治疗耐药菌肺部感染的临床疗效及安全性。方法:通过检索国家知识基础设施数据库(CNKI)、中国学术期刊数据库(CSPD)、中文科技期刊数据库(CCD)、中国生物医学文献数据库(CBM)、Pubmed、Embase及Cochrane Library数据库,搜集有关痰热清注射液治疗耐药菌感染的随机对照试验,并采用StataSE软件进行Meta分析。结果:痰热清注射液联合西药治疗耐药菌肺部感染能提高临床总有效率(RR=1.223,95%CI为1.138~1.314,P=0.000),提高临床治愈例数(MD=5.215,95%CI为2.347~8.878,P=0.000）,及减少临床治愈时间(MD=-1.948,95%CI为-2.850~-1.046,P=0.009),差异均有统计学意义。结论:痰热清注射液治疗耐药菌肺部感染有较好的疗效和安全性。 |
| English Summary: |
| To evaluate the clinical efficacy and safety of Tanreqing Injection combined with western medicine in the treatment of drug-resistant pulmonary infection.Methods:CNKI，CSPD，CCD，CBM，PubMed，Embase，and Cochrane Library were searched for the randomized controlled trials(RCTs) of Tanreqing Injection in the treatment of drug-resistant infections.Meta-analysis was carried out by using StataSE.Results:Tanreqing Injection combined with western medicine in the treatment of drug-resistant pulmonary infection could improve the total clinical effective rate[RR=1.223，95% CI(1.138 to 1.314)，P=0.000]，increase the number of cured cases[MD=5.215，95% CI(2.347 to 8.878)，P=0.000]，and shorten the clinical treatment time[MD=-1.948，95% CI(-2.850 to -1.046)，P=0.009].Conclusion:Tanreqing Injection possesses good efficacy and safety in the treatment of drug-resistant pulmonary infection. |
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