Dampness is one of the six climatic factors(wind，cold，heat，dampness，dryness and fire) which are pathogenic factors.Dampness syndrome is directly caused by dampness accumulation in the body.In recent years，the syndrome has been the hot spot and focus of research on traditional Chinese medicine(TCM) syndromes.Syndrome development serves as a bridge between TCM and modern medicine.It is the foundation for further clinical and basic research to develop animal models that can objectively reflect dampness syndrome.At the moment，there has been an explosion of research on dampness syndrome，especially the animal modeling and the detection of related indicators.This article aims to summarize the theories on dampness syndrome，classification of related animal models，and evaluation indicators and significance of the models，which is expected to serve as a reference for the modeling of dampness syndrome，optimization of related models，and study of the biological mechanism of the syndrome.