To explore the main active components of Suhuang Zhike Capsules(SH),identify the targets and signaling pathways,analyze the multi-target and multi-pathway intervention mechanism in the treatment of cough variant asthma(CVA),and clarify the pharmacodynamic material basis and mechanism of action of SH based on molecular docking method and network pharmacology.Methods:Based on the network pharmacology and molecular docking,active components of SH were screened out and the corresponding pathways were analyzed.Results:Seventy-five active components were screened out from SH,and Ephedrae Herba and Peucedani Radix contained the largest proportions of components,16 for each one,followed by Perillae Fructus for 13,Eriobotryae Folium for 11,Schisandrae Chinensis Fructus for 7,Arctii Fructus for 5,Pheretima for 4,and Perillae Folium for 3.In addition,a total of 429 targets related to CVA and 316 pathways were obtained,including two disease-related signaling pathways,four inflammation-related pathways,and one protection pathway against lung injury.Conclusion:The present study preliminarily discussed the main active components,related targets,and pathways involved in SH and predicted the pharmacodynamic material basis and mechanism of SH against CVA,which is expected to provide references and material basis for the subsequent optimization of prescription modification and research on the efficacy evaluation indexes in the clinical treatment of CVA.