| 引用本文:李奕1，张曦元1,2，庞博1，花宝金1.胰腺癌从“调气解毒”立论的中医药治疗策略与实践[J].世界中医药,2022,(11):. |
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| 胰腺癌从“调气解毒”立论的中医药治疗策略与实践 |
| Strategy and Practice of Traditional Chinese Medicine Treatment for Pancreatic Cancer from the Viewpoint of Regulating Qi and Removing Toxin |
| 投稿时间：2022-04-20 |
| DOI：10.3969/j.issn.1673-7202.2022.11.002 |
| 中文关键词: 胰腺癌 调气解毒 炎癌转化 分期治疗 气机升降 治未病 学术思想 中医药 |
| English Keywords:Pancreatic cancer Regulating qi and detoxifying Inflammation-cancer transformation Staged treatment Ascending and descending of qi movement Treating disease before its onset Academic thought Traditional Chinese medicine |
| 基金项目:中国中医科学院科技创新工程项目（CI2021B009，CI2021A01805）；中医药创新团队及人才支持计划项目（国中医药人教函〔2022〕8号）；北京市科学技术委员会首都临床诊疗技术研究及示范应用专项（Z191100006619022） |
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| 中文摘要: |
| 胰腺癌是消化系统常见的恶性肿瘤，其侵袭、转移性极强，目前常规的手术及放疗、化疗等治疗手段皆不能取得理想的临床疗效。本研究在全面继承团队老一辈专家“扶正培本”肿瘤治疗学术思想的基础上，围绕胰腺癌病位、病机、病势特点及本虚标实的特征，从调节气机、消解癌毒层面入手，创新性地提出以“调气解毒”立论的胰腺癌中医药治疗策略。从气机升降与抗癌解毒的不同维度，解析肿瘤形成、演变、扩散、转移的病理过程。在结合胰腺癌疾病自然病程特点的基础上，依据炎癌转化期、气聚成癌期、缓解康复期等不同病期特点，构建控上游、治病本、防下游的肿瘤全周期分期诊疗思维框架。胰腺癌分期诊疗的思维方法为中医药的有效介入提供了更加精准有效的方案，是肿瘤研究学术思想的开拓创新，同时也是探寻胰腺癌核心病机、优化治疗方案、回归证治本源的多元融合。 |
| English Summary: |
| Pancreatic cancer is a common malignant tumor in the digestive system,with extremely strong invasion and metastasis.At present,conventional surgery,radiotherapy and chemotherapy fail to achieve desirable clinical efficacy.Therefore,based on the comprehensive academic thinking of reinforcing health qi and consolidating root,and focusing on the disease location,pathogenesis and disease trend of pancreatic cancer as well as the characteristics of root deficiency and branch excess,we innovatively proposed the strategy of traditional Chinese medicine treatment for pancreatic cancer from the perspective of regulating qi and removing toxin.The pathological processes of tumor formation,evolution,diffusion and metastasis were analyzed from different dimensions of ascending and descending of qi movement,resisting cancer and detoxifying.Combined with the natural course of pancreatic cancer and according to the characteristics of different disease stages,such as inflammation-cancer transformation stage,qi accumulation-cancer formation stage and remission-rehabilitation stage,we built a thinking framework of tumor whole-cycle staging diagnosis and treatment to control the upstream,treat disease root and prevent the downstream.This thinking method provided an accurate and effective scheme for the intervention of traditional Chinese medicine.It was a pioneering and innovative idea of cancer research,and also a multi-element fusion for exploring the core pathogenesis of pancreatic cancer,optimizing the treatment plan and returning to root cause of the disease for treatment. |
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