To observe the clinical efficacy of Nie Jinmaiwei massage in preventing nausea and vomiting caused by cisplatin-included chemotherapy regimens.Methods:A total of 65 cases who received cisplatin-included chemotherapy regimens in Guang'anmen Hospital,China Academy of Chinese Medical Sciences from April 2019 to January 2020 were selected as research subjects.They were divided into observation group(n=34) and control group(n=31) according to the order of admission.In addition to intravenously administered ondansetron in both groups,the observation group was given Nie Jinmaiwei massage and the control group received sham massage treatment.The chemotherapy-induced vomiting control rate(CIV-CR),chemotherapy-induced nausea control rate(CIN-CR),complete control rate(CCR),severity of nausea,number of vomiting and quality of life(QoL) in acute and delayed phases were compared between the two groups.Results:Compared with the control group,the observation group had 27.8% increase in delayed CIV-CR(P=0.018),and 27.4% in delayed CIN-CR(P=0.022),and the number of vomiting and the severity of nausea were less in the observation group than those in the control group(1.1 vs.5.0,P=0.013; 2.2 vs.3.9,P=0.016,respectively) in delayed phase.However,there were no differences in CIV-CR(P=0.413),CIN-CR(P=0.804),CCR(P=0.152),number of vomiting(P=0.308) and severity of nausea(P=0.514) in acute phase.Furthermore,Nie Jinmaiwei massage improved QoL(90.7 vs.83.5,P=0.003),especially in terms of functional well-being(24.1 vs.21.9,P=0.023).Conclusion:Nie Jinmaiwei massage combined with ondansetron for chemotherapy-included nausea and vomiting could improve CIN-CR,CIV-CR and QoL,and decrease the number of vomiting and the severity of nausea in delayed phase..