To analyze the acupoint selection regularity for acupuncture and moxibustion in the treatment of chronic nonspecific low back pain(CNLBP).Methods:The randomized controlled trials(RCTs) on acupuncture and moxibustion in the treatment of CNLBP published from database inception to December 31，2020，were retrieved from CNKI，CSPD，and CCD.The acupoints and acupuncture and moxibustion prescriptions against CNLBP were summarized and statistically analyzed to establish a database.The acupuncture and moxibustion prescriptions underwent cluster analysis and correlation analysis by IBM SPSS 25.0，Climentine 12.0，and Python.Results:Eighty research articles were included，involving 80 acupuncture and moxibustion prescriptions and 95 acupoints.The most commonly used acupoints were Shenshu(BL 23)，Weizhong(BL 40)，Dachangshu(BL 25)，ashipoint，Yaoyangguan(GV 3)，and Jiaji(EX-B 2).The most frequently used meridian was bladder meridian of foot-Taiyang.Acupoints were mainly concentrated in the back and lower extremities.The commonly used specific acupoints were five transport points，back transport point，and crossing points.Correlation analysis showed that the combination of Shenshu(BL 23) and Dachangshu(BL 25) played an important role in the acupuncture and moxibustion treatment of CNLBP.Conclusion:Acupuncture and moxibustion treatment of CNLBP follows the principle of selecting acupoints according to meridians and syndrome differentiation，with the assistance of specific acupoints.