To explore the medication rules of Mongolian medicine prescriptions.Methods:Common Mongolian medicine prescriptions were comprehensively collected and screened from Drug Standards of the Ministry of Health of the People's Republic of China·Mongolian Medicines,Encyclopedia of Chinese Medicine·Mongolian Medicine,Traditional Mongolian Medicine and Prescription,and Mongolian Medicine Prescription(Mongolian medicine textbooks in Mongolian).Frequency statistics,association rules and cluster analysis were carried out from the perspectives of dosage form,prescription type,medication frequency,drug classification,property flavor and efficacy to explore the medication rules of the prescriptions.Results:A total of 524 common Mongolian prescriptions were screened,with powder as the most commonly used dosage form,and five zang-organ prescriptions the main prescription types.The high-frequency medicinal materials were Fructus Chebulae,Flos Carthami and Fructus Gardeniae,and those for Badagan treatment had the highest frequency,accounting for 16.36%,followed by antipyretic medicines and tranquilizing Heyi medicines.The medicines were mainly cool in property(43.33%) and bitter in flavor(45.55%),and the frequency of lightness in drug efficacy was the highest,accounting for 41.39%,followed by bluntness,dryness and roughness.Of the 19 high-frequency drug pairs,13 were related to tranquilizing Heyi,and among the nine core drug combinations,Fructus Meliae Toosendan→Fructus Gardeniae had the highest confidence.Six drug combinations were obtained by cluster analysis,including four cool combinations and two warm combinations.Conclusion:In Mongolian medicine,powder was frequently adopted and the treatment focused on five zang-organs,with Fructus Chebulae selected mostly.The prescriptions were developed aiming at the six basic symptoms,and cool and bitter medicines with lightness,bluntness,dryness and roughness were mostly chosen.For drug pairs,those for tranquilizing Heyi were dominant,and the core drug combination with the highest confidence was Fructus Meliae Toosendan→Fructus Gardeniae.Cluster combinations were dominated by coolness,and mutually validated with the medicinal results.