| 引用本文:王丹1，车文文1，杨静雯1，夏小军2，姜小燕2，王平3，潘战宇3，马尧4，王斌3，吕中茜1,5,6，潘兴芳5,6，赵美丹5,6，赵天易5,6，陈泽林5,6，郭永明1,5,6，史丽萍7，陈波1,5,6，郭义1,6,7.针灸防治肿瘤相关性抑郁状态的临床实践指南研究[J].世界中医药,2022,(14):. |
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| 针灸防治肿瘤相关性抑郁状态的临床实践指南研究 |
| Clinical Application Guidelines of Acupuncture in Prevention and Treatment of Cancer-related Depression |
| 投稿时间：2021-03-09 |
| DOI：10.3969/j.issn.1673-7202.2022.14.014 |
| 中文关键词: 针刺 艾灸 肿瘤相关性抑郁状态 三证合一 临床实践指南 临床方案 证据整合与推荐 |
| English Keywords:Acupuncture Moxibustion Cancer-related depression Unity of three evidence Clinical practice guidelines Clinical scheme Evidence integration and recommendation |
| 基金项目:国家重点研发计划“中医药现代化研究”重点专项（2019YFC1712200，2019YFC1712204）——国际针灸技术操作规范研制；2020年度中医药标准化项目（GZT-FJS-2020-202）——标准化人才培养模式的构建及实施应用研究；中国科协第五届中国科协青年人才托举工程（2019-2021ZGZJXH-QNRC001） |
| 作者 | 单位 | | 王丹1，车文文1，杨静雯1，夏小军2，姜小燕2，王平3，潘战宇3，马尧4，王斌3，吕中茜1,5,6，潘兴芳5,6，赵美丹5,6，赵天易5,6，陈泽林5,6，郭永明1,5,6，史丽萍7，陈波1,5,6，郭义1,6,7 | 1 天津中医药大学实验针灸学研究中心，天津，300000； 2 甘肃省肿瘤医院乳腺科，兰州，730000； 3 天津医科大学肿瘤医院国家肿瘤临床医学研究中心，天津，300000； 4 内蒙古医学院第二附属医院，呼和浩特，010000； 5 天津中医药大学针灸推拿学院，天津，300000； 6 国家中医针灸临床医学研究中心，天津，300000； 7 天津中医药大学中医学院，天津，300000 |
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| 中文摘要: |
| 目的:探索针灸防治肿瘤相关性抑郁状态的临床实践方案，为制定临床实践指南提供依据。方法:人工检索49本古代医籍，收集关于针灸疗法治疗抑郁的古代文献证据；计算机检索国家知识基础设施数据库（CNKI）、中国医学生物文献数据库（CBM）、中国学术期刊数据库（CSPD）及中文科技期刊数据库（CCD）、Pubmed、EMBASE、Cochrane Library等数据库，全面收集针灸疗法治疗肿瘤相关性抑郁的现代文献证据；制定发放《针灸干预肿瘤相关性抑郁状态调查问卷》，收集针灸干预肿瘤相关性抑郁状态的现代专家经验。通过整合3方面证据形成针灸防治肿瘤相关性抑郁状态临床推荐方案。结果:古代医籍文献相关条目共14项；现代文献共检索到137篇文献，通过对文献进行纳入排除，最终纳入14篇现代文献，包括中文文献8篇，英文文献6篇；临床专家问卷共收回52份。综合3方面研究结果发现针灸治疗肿瘤相关性抑郁状态常用毫针针刺、电针、艾灸、耳穴贴压等疗法；常用穴位为神门、内关、印堂、百会、合谷、足三里、气海、三阴交、阴陵泉、太冲、肝俞、太溪、肾俞、心俞等。结论:综合3方面证据形成针灸防治肿瘤相关性抑郁状态的临床推荐应用方案，弱推荐使用毫针针刺、电针、艾灸、耳穴贴压疗法；推荐使用穴位为神门、内关、印堂、百会、合谷、足三里、气海、三阴交、阴陵泉、太冲、肝俞、太溪、肾俞、心俞等。 |
| English Summary: |
| To explore the clinical application of acupuncture in the prevention and treatment of cancer-related depression,and provide references for the development of clinical practice guidelines.Methods:Forty-nine ancient medical books were searched manually,and the ancient literature evidence of acupuncture treatment of depression was collected.Databases including China National Knowledge Infrastructure(CNKI),China Biology Medicine disc(CBMdisc),China Science Periodical Database(CSPD),Chinese Citation Database(CCD),PubMed,EMBASE,and Cochrane Library were retrieved by computer to comprehensively collect the modern literature evidence of acupuncture treatment of cancer-related depression.The questionnaire on acupuncture intervention on cancer-related depression was formulated and distributed to collect the experience of modern specialists in the acupuncture intervention of cancer-related depression.The three aspects of evidence were integrated to form the clinically recommended scheme of the prevention and treatment of cancer-related depression by acupuncture.Results:After sorting out the literature,14 items of ancient literature and 137 items of modern literature were retrieved,including 8 Chinese papers and 6 English papers.Fifty-two questionnaires for the clinical specialists were collected.The comprehensive research results from the three aspects found that acupuncture treatment of cancer-related depression commonly used filiform needle acupuncture,electro-acupuncture,moxibustion,auricular acupoint pressing,and other therapies.The commonly-used acupoints were Shenmen,Neiguan,Yintang,Baihui,Hegu,Zusanli,Qihai,Sanyinjiao,Yinlingquan,Taichong,Ganshu,Taixi,Shenshu,and Xinshu.Conclusion:Based on the evidence from the three aspects,the recommended clinical application scheme for the prevention and treatment of cancer-related depression by acupuncture is formed.Filiform needle acupuncture,electro-acupuncture,moxibustion,and auricular acupoint pressing are weakly recommended.Shenmen,Neiguan,Yintang,Baihui,Hegu,Zusan,Qihai,Sanyinjiao,Yinlingquan,Taichong,Ganshu,Taixi,Shenshu,and Xinshu are recommended. |
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