To explore the medication rules of the treatment of chronic atrophic gastritis via the Traditional Chinese Medicine Inheritance Platform.Methods:The relevant literature on the application of Chinese medicinal prescriptions for the treatment of chronic atrophic gastritis were searched against CNKI and Wanfang Data.All the extracted prescriptions were analyzed via the Traditional Chinese Medicine Inheritance Platform to reveal the medication rules and analyze the new prescriptions obtained.Results:A total of 207 prescriptions related to chronic atrophic gastritis were collected.After excluding duplicates and unreasonable prescriptions,180 prescriptions to be analyzed were obtained,involving 203 Chinese herbal medicines.Among them,there were 32 Chinese medicines with a frequency of ≥20.The top five herbal medicines were Poria(89),Codonopsis Radix(85),Atractylodis Macrocephalae Rhizoma(84),Astragali Radix(63),and Glycyrrhizae Radix et Rhizoma Praeparata cum Melle(61).Most of the used herbal medicines are sweet and warm and have the effects of tonifying,regulating qi,and promoting digestion,with the tropism to the spleen and stomach meridians.The top five high-frequency herb pairs were Atractylodis Macrocephalae Rhizoma-Poria(63),Codonopsis Radix-Poria(56),Codonopsis Radix-Atractylodis Macrocephalae Rhizoma(54),Citri Reticulatae Pericarpium-Poria(47),and Glycyrrhizae Radix et Rhizoma Praeparata cum Melle-Poria(46).Furthermore,68 core combinations of 3 herbs,14 core combinations of 4 herbs,and 12 new prescriptions were obtained.Conclusion:The treatment of chronic atrophic gastritis mainly follows the principle of replenishing qi and invigorating spleen,regulating qi and promoting digestion,while taking into account removing dampness and resolving phlegm,which provides theoretical support for the clinical development of new prescriptions.