| 引用本文:仇敏1，谢慧娟1，罗传红1，李格菲1，张定堃1，樊三虎2，黄浩洲1，林俊芝3.基于多酚质量传递规律视角下的余甘子质量标准研究思路[J].世界中医药,2022,(19):. |
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| 基于多酚质量传递规律视角下的余甘子质量标准研究思路 |
| Research Ideas on Quality Standards of Phyllanthus emblica from the Perspective of Polyphenol Mass Transfer Law |
| 投稿时间：2022-08-26 |
| DOI：10.3969/j.issn.1673-7202.2022.19.004 |
| 中文关键词: 余甘子 质量标准 没食子酸 鞣花酸 质量传递规律 |
| English Keywords:Phyllanthus emblica Quality standard Gallic acid Ellagic acid Mass transfer law |
| 基金项目:国家自然科学基金项目(81973493);四川省中医药标准化研究项目(2019073);三勒浆药业-成中医联合实验室项目(2019-YF04-00086-JH) |
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| 中文摘要: |
| 余甘子是我国西南地区特色药食同源品种。目前,余甘子质控标准国际上可参考的主要有《英国药典》《印度药典》《香港中药材标准》和《中华人民共和国药典》,主要以没食子酸和鞣花酸为评价指标。然而,作为余甘子重要药效物质基础的多酚(鞣质)在贮藏和加工过程中具有特殊的转化与传递规律。现有质量评价方法仅以没食子酸和鞣花酸作为评价指标,难以合理有效评价余甘子的质量。为此,本文基于余甘子多酚成分转化传递规律,结合余甘子应用现状及现有余甘子药典标准,对余甘子质量标准研究思路与制定进行探讨。 |
| English Summary: |
| Phyllanthus emblica is a characteristic medicinal food species in southwest China.At present，the main international reference standards for P.emblica quality control are British Pharmacopoeia，Indian Pharmacopoeia，Hong Kong Standards for Chinese Medicinal Materials，and Pharmacopoeia of the People's Republic of China，mainly based on gallic acid and ellagic acid as evaluation indicators.However，polyphenols(ellagitannins)，which are the important medicinal substances in P.emblica，have special transformation and transmission rules during storage and processing.The existing quality evaluation methods only use gallic acid and ellagic acid as evaluation indexes，which are difficult to evaluate the quality of P.emblica reasonably and effectively.Therefore，this paper discussed the research ideas and development of P.emblica quality standards based on the mass transfer laws of P.emblica polyphenol components，combined with the current situation of P.emblica applications and existing standards of P.emblica in the pharmacopeia. |
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