| 引用本文:何伟1，2，3，王莉1，2，3，刘磊1，3，黄景凤1，2，3，李治建4.罗布麻茶改善睡眠功能实验研究[J].世界中医药,2022,(23):. |
|
| 罗布麻茶改善睡眠功能实验研究 |
| Apocynum venetum Tea Improves Animal Sleep |
| 投稿时间：2020-12-05 |
| DOI：10.3969/j.issn.1673-7202.2022.23.014 |
| 中文关键词: 罗布麻茶 小鼠 戊巴比妥钠 巴比妥钠 催眠实验 潜伏期 功效评价 改善睡眠 |
| English Keywords:A.venetum tea Mice Sodium pentobarbital Barbital sodium Hypnosis experiment Sleep latency Functional evaluation Improving sleep |
| 基金项目:新疆维吾尔自治区重大科技专项项目（2016A03006，2016A03006-2，2016A03006-4） |
|
| 摘要点击次数: 491 |
| 全文下载次数: 0 |
| 中文摘要: |
| 目的：研究罗布麻茶改善睡眠功效。方法：通过小鼠经口连续灌胃给予高剂量、中剂量和低剂量3种不同剂量的罗布麻茶30 d，然后对给药后小鼠的戊巴比妥钠直接睡眠的实验、戊巴比妥钠阈下剂量的催眠实验、巴比妥钠睡眠潜伏期实验对罗布麻茶功效进行评价。结果：与阴性对照组比较，戊巴比妥钠诱导的小鼠睡眠时间罗布麻茶高剂量组显著延长（P<0.01），睡眠潜伏期明显减短（P<0.01）；罗布麻茶中剂量组小鼠睡眠时间延长（P<0.05）；直接睡眠实验入睡动物个数、睡眠时间及戊巴比妥钠入睡发生率罗布麻茶高剂量组、罗布麻茶中剂量组、罗布麻茶低剂量组与阴性对照组比较差异无统计学意义（P>0.05）；各项实验小鼠体质量罗布麻茶高剂量组、罗布麻茶中剂量组、罗布麻茶低剂量组与阴性对照组比差异无统计学意义（P>0.05）。结论：罗布麻茶具有改善睡眠的功效。 |
| English Summary: |
| To explore the effect of A.venetum tea(AVT) on sleep of mice.Methods:Mice received(oral administration) high-dose，medium-dose，and low-dose AVT for 30 days.Then，sodium pentobarbital-induced sleep experiment，hypnosis experiment under subthreshold dose of sodium pentobarbital，and barbital sodium sleep latency experiment were adopted to evaluate the function of AVT.Results:The sodium pentobarbital-induced sleep time was longer(P<0.01) and sleep latency was shorter(P<0.01) in the high-dose AVT group than in the negative control group.The sleep time in the medium-dose AVT group was longer than the negative control group(P<0.05).The number of sleeping mice，sleep time，and occurrence of sodium pentobarbital-induced sleep in the negative control group were insignificantly different from those in the three AVT groups(P>0.05).There was no significant difference in body weight between the negative control group and the three AVT groups(P>0.05).Conclusion:AVT had the effect of improving sleep. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
