世界中医药
文章摘要
引用本文:戴胜云1,张荣林2,马双成1,谢培德3,郑健1,林雀跃3.民族药材小叶金花草的研究现状与思考[J].世界中医药,2023,(07):.  
民族药材小叶金花草的研究现状与思考
Research Progress in the Ethnic Medicinal Herb Onychium japonicum
投稿时间:2021-11-11  
DOI:10.3969/j.issn.1673-7202.2023.07.011
中文关键词:  民族药  小叶金花草  质量标准  资源分布  分子生物学  化学成分  药理作用  标准提高
English Keywords:Ethnic medicinal herb  Onychium japonicum  Quality standard  Resource distribution  Molecular biology  Chemical composition  Pharmacological effect  Standard improvement
基金项目:“十三五”国家科技重大专项课题重大新药创制项目(2017ZX09301060-011)——驱虫斑鸠菊等代表性民族药材的质量评价关键技术研究子课题“壮药材小叶金花草的质量评价研究”(2017ZX09301060-011-002)
作者单位
戴胜云1,张荣林2,马双成1,谢培德3,郑健1,林雀跃3 1 中国食品药品检定研究院北京102629 2 广西-东盟食品检验检测中心南宁530021 3 广西壮族自治区食品药品检验所南宁530021 
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中文摘要:
      小叶金花草为中国蕨科金粉蕨属植物野鸡尾[Onychium japonicum(Thunb.)Kze.]的干燥全草,别名野鸡尾、金花草、旋鸡尾等,为民间习用草药,具有清热解毒,止血,利湿等功效,常用于风热感冒,肺热咳嗽,急性胃肠炎,痢疾等疾病的治疗。小叶金花草始载于《植物名实图考》,在广西地区作为常用的壮、瑶药材,在湖北西部地区也常作为土家族常用草药,在贵州少数民族聚集区是常用的止血药,是极具民族色彩的药材。小叶金花草曾收载于《中华人民共和国药典》1977年版,名为“小野鸡尾”,由于民族药的研究基础薄弱,且为民间习用,关于小叶金花草的研究较少。小叶金花草是广西国际壮医医院的临床经验方柏金颗粒的主要药味,经该院多年临床验证适用于高尿酸血症的治疗,疗效显著,但目前小叶金花草的质量标准有待于提高以便于推广使用。现对小叶金花草的发展历史及研究进展进行总结,包括质量标准、资源分布、生药学、分子生物学、化学成分和药理作用等内容,以期为民族药小叶金花草的质量标准完善和提高提供参考,也为进一步促进民族药资源开发奠定基础。
English Summary:
      Herba Onychii Japonici,the dried herb of Onychium japonicum(Thunb.) Kze.,is an ethnic herbal medicine with the functions of clearing heat,removing toxin,stopping bleeding,and eliminating dampness.It is commonly used in the treatment of wind-heat common cold,cough caused by lung heat,acute gastroenteritis,dysentery and other diseases.This herb was firstly recorded in Illustrated Reference of Botanical Nomenclature(Zhi Wu Shi Ming Tu Kao) and used by the people of Zhuang and Yao ethnic minorities in Guangxi,the people of Tujia ethnic minority in western Hubei,and as a bleeding-stopping medicine in the ethnic minority gathering area in Guizhou.O.japonicum was once recorded in the Chinese Pharmacopoeia(1977 Edition).The research on this herb is insufficient due to the weak research foundation of ethnic herbs and folk usage.O.japonicum is the main herb used in the Baijin Granules developed by the Guangxi International Zhuang Medicine Hospital based on clinical experience.This formula has been proved suitable and effective for the treatment of hyperuricemia by years of clinical trials.However,the quality standard of O.japonicum needs to be improved to facilitate the promotion.This paper summarized the development history and research progress of O.japonicum from quality standards,resource distribution,pharmacognosy,molecular biology,chemical composition,and pharmacological effects,aiming to provide reference for improving the quality standards of O.japonicum and lay a foundation for further development and utilization of the ethnic medicinal resources.
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