To investigate the syndrome-related predictors of cardiovascular events in the patients with stable coronary heart disease.Methods:A retrospective study was conducted on the clinical data of the patients with stable coronary heart disease from October 2016 to April 2018.A total of 2 856 patients were enrolled in this study,including 96 patients who had cardiovascular events within 6 months after the first visit(observation group) and 2 760 patients who had no cardiovascular events(control group).The data of general information,dietary habits,symptoms,and TCM syndrome of the patients were collected.Single factor analysis and multivariate logistic regression were employed to explore the syndrome-related predictors.Results:The incidence of cardiovascular events within 6 months in the patients with stable coronary heart disease was 3.36%.The results of single factor analysis showed that sex,marital status,regularity of dietary habits,preference for spicy food,dry scaly skin,cyanosis at the end of limbs,astringent pulse,difficulty in falling asleep,dizziness,heaviness of head,red cheeks,dark eye circles,irritability,abnormal tongue coating,deep pulse,syndrome of yin deficiency,and syndrome of heat stagnation were the predictors of cardiovascular events in the patients with stable coronary heart disease(P<0.05).The results of multivariate logistic regression showed that male patients(OR=1.64,95%CI 1.03 to 2.62,P=0.04),abnormal tongue coating(OR=1.91,95%CI 1.12 to 3.25,P=0.02),irritability(OR=1.88,95%CI 1.22 to 2.88,P<0.01),deep pulse(OR=2.41,95%CI 1.5 to 3.96,P<0.01),and red cheeks(OR=2.46,95%CI 1.49 to 3.91,P<0.01) were predictors and preference for spicy food(OR=0.33,95%CI 0.13 to 0.85,P=0.02) was the protective factor for cardiovascular events in the patients with stable coronary heart disease.Conclusion:In addition to the common predictors in western medicine,syndrome-related factors also demonstrate the potential of predicting cardiovascular events in the patients with stable coronary heart disease,which deserves attention and remains to be studied.