| 引用本文:张宗金1，王悦芬1，赵文景1，崔方强1，孟元1，沈存1，孙雪艳1，申子龙1，唐珑1，李平2.基于邪伏膜原理论研究中医药治疗糖尿病肾病[J].世界中医药,2023,(11):. |
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| 基于邪伏膜原理论研究中医药治疗糖尿病肾病 |
| TCM Treatment of Diabetic Nephropathy Based on Theory of Latent Pathogen in Pleurodiaphragmatic Interspace |
| 投稿时间：2021-11-18 |
| DOI：10.3969/j.issn.1673-7202.2023.11.013 |
| 中文关键词: 膜原 邪伏膜原 糖尿病肾病 肾小球疾病 晚期糖基化终末产物 保肾方 三焦 中医药治疗 |
| English Keywords:Pleurodiaphragmatic interspace Latent pathogen in pleurodiaphragmatic interspace Diabetic nephropathy Glomerular disease Advanced glycation end products Baoshen Prescription Triple energizer Traditional Chinese medicine treatment |
| 基金项目:北京市自然科学基金项目(7172096);北京市中医药科技发展资金项目(JJ-2020-46) |
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| 中文摘要: |
| 糖尿病肾病（DN）是导致终末期肾脏病的重要原因之一。代谢记忆学说背景下,晚期糖基化终末产物沉积于肾脏,导致疾病移时后发、迁延难愈与中医邪伏膜原理论相吻合。现基于邪伏膜原学说,提出DN气阴不足、气化不利、痰瘀互结、邪伏膜原的病机。治疗方面,在透达膜原的基础上,重视三焦的畅通。从邪伏膜原角度论治DN,扩展了邪伏膜原学说的应用范畴,开拓了中医药治疗DN的新思路。 |
| English Summary: |
| Diabetic nephropathy(DN) is one of the important causes of end-stage renal disease.In the context of the metabolic memory theory，advanced glycation end products(AGEs) deposit in the kidneys，leading to a delayed and difficult-to-cure progression of the disease，which coincides with the theory of latent pathogen in pleurodiaphragmatic interspace in traditional Chinese medicine(TCM).Based on the theory of latent pathogen in pleurodiaphragmatic interspace，it was proposed that the pathogenesis of DN involved insufficiency of qi and yin，impaired qi transformation，mutual obstruction of phlegm and stasis，and latent pathogen in pleurodiaphragmatic interspace.In terms of treatment，emphasis is placed on promoting the unobstructed flow of the triple energizer.In this study，DN was treated from the perspective of latent pathogen in pleurodiaphragmatic interspace.The application scope of this theory was expanded，and new ideas for the TCM treatment of DN were explored. |
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