To study the acupoint selection rules in acupuncture and moxibustion treatment of cognitive impairment in Parkinson's disease(PDCI) based on data mining and provide evidence for clinical diagnosis and treatment.Methods:CNKI，CBM，CSPD，CCD，PubMed，Embase，and Web of Science were searched for relevant literature on acupuncture and moxibustion treatment of PDCI published between January 2000 and November 2021，and an acupoint prescription database was established.Data analysis was conducted using statistical software such as SPSS Modeler 18.0 and SPSS 25.0.Results:A total of 22 articles were included，containing 39 acupoint prescriptions，involving 108 acupoints(including extra points and scalp acupuncture points).The most commonly selected acupoint was Baihui(GV20)，and the commonly selected meridians and collaterals were the governor vessel(GV)，foot lesser yang gallbladder meridian(GB)，and conception vessel(CV).Common acupoint combinations included Baihui(GV20)-Sishencong(EX-HN 1)-Xuanzhong(GB39) and Baihui(GV20)-Yintang(EX-HN 3)-Fengchi(GB20).Conclusion:Acupuncture and moxibustion treatment for PDCI emphasizes treating the root cause and manifestations simultaneously，with flexible and skillful acupoint selection and consideration of multiple meridians and collaterals and organ harmonization.