引用本文:陈荷莹,刘毅,刘会珍,陈佳倩,金晨,黄慧莲.落新妇苷的稳定性及生物活性研究进展[J].世界中医药,2023,(11):. |
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落新妇苷的稳定性及生物活性研究进展 |
Research Progress on the Stability and Biological Activity of Astilbin |
投稿时间:2022-04-08 |
DOI:10.3969/j.issn.1673-7202.2023.11.021 |
中文关键词: 落新妇苷 化学结构 稳定性 纯化技术 药代动力学 生物活性 选择性免疫抑制 研究进展 |
English Keywords:Astilbin Chemical structure Stability Purification technology Pharmacokinetics Biological activity Selective immunosuppression Research progress |
基金项目:国家自然科学基金项目(82160792);江西省教育厅项目(GJJ201214);江西省创新创业计划项目(202210412545) |
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中文摘要: |
落新妇苷是二氢黄酮醇苷类化合物,是土茯苓中最主要的活性物质,具有选择性免疫抑制、抗氧化、抗炎、降血脂等多种生物活性。对落新妇苷做了大量实验研究,为该新候选药物的研发提供了科学依据。通过查阅大量相关文献,对落新妇苷的稳定性研究和药理活性进行系统总结,为其进一步的深入研究和开发利用提供参考。 |
English Summary: |
Astilbin is a dihydroflavonol glycoside and the major active component in Smilacis Glabrae Rhizoma.It exhibits various biological activities,including selective immunosuppression,antioxidant,anti-inflammatory,and lipid-lowering effects.Extensive experimental research has been conducted on astilbin,providing a scientific basis for the development of this new candidate drug.By reviewing a large number of relevant literature,this study systematically summarized the stability and pharmacological activities of astilbin,providing references for further in-depth research and development of its utilization. |
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