经典名方苏合香丸治疗中风临床精准定位研究的专家问卷调查
CSTR:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

基金项目:

国家自然科学基金项目(82104823);中华中医药学会项目(2021XS-001-02,2021XS-001-05);北京市科技新星计划项目(Z211100002121061)


Clinical Precise Positioning of Classic Prescription Suhexiang Pills in the Treatment of Stroke:An Expert Questionnaire Survey and Analysis
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:通过问卷调查深入挖掘临床专家应用苏合香丸治疗中风的临证经验,初步明确苏合香丸适用人群及安全性,推动下一阶段真实世界研究方案的设计与优化。方法:2021年8月至2021年10月在全国范围内开展针对临床医师的问卷调查,并对调查结果进行统计分析。结果:共回收问卷231份,受访专家具有较好的代表性及权威性。苏合香丸适应证、禁忌证、适用阶段等临床问题是专家关注重点。在中医适应证方面,多数专家认为中风-中经络证(82.3%)、中脏腑-阴闭证(70.6%)为苏合香丸临床适用诊断。在西医适应证方面,专家普遍认为缺血性脑卒中(97.4%)和出血性脑卒中患者(93.9%)均适用苏合香丸。在干预时点及疗程方面,发病<12 h即可应用苏合香丸(61.0%),最佳疗程<14 d(74%)。在药物安全性方面,妊娠(79.2%)及过敏(78.8%)为苏合香丸主要禁忌证。苏合香丸存在肝功能损伤(61.0%)、肾功能损伤(59.3%)风险。结论:专家普遍认为苏合香丸临床适用于治疗痰湿蒙窍导致出现神志昏蒙、头昏头晕、喉中痰鸣等临床表现的缺血性及出血性脑卒中患者,可用于以急性期为主的中风各临床阶段。苏合香丸芳香耗气,临床不宜久用,妊娠、过敏为苏合香丸禁忌证。同时,临床应用应充分考虑朱砂所致的肝肾毒性。

    Abstract:

    To explore the clinical experience of experts in the application of Suhexiang Pills for the treatment of stroke through a questionnaire survey,identify the target population and assess the safety of Suhexiang Pills,and facilitate the design and optimization of the next phase of real-world research protocols.Methods:A nationwide questionnaire survey targeting clinical physicians was conducted from August 2021 to October 2021,and the survey results were statistically analyzed.Results:A total of 231 questionnaires were collected,and the interviewed experts were considered representative and authoritative.Clinical issues of concern to experts included indications,contraindications,and applicable stages for Suhexiang Pills.In terms of traditional Chinese medicine(TCM) indications,the majority of experts believed that Suhexiang Pills were clinically applicable for stroke with wind striking meridian and collateral syndrome(82.3%) and yin blockage in organ stroke syndrome(70.6%).In terms of western medicine indications,experts generally agreed that Suhexiang Pills were suitable for both ischemic stroke patients(97.4%) and hemorrhagic stroke patients(93.9%).Regarding the timing and duration of intervention,61.0% of experts indicated that Suhexiang Pills could be used within 12 hours after onset,and the optimal treatment duration was less than 14 days(74%).In terms of safety,pregnancy(79.2%) and allergies(78.8%) were identified as the main contraindications for Suhexiang Pills.There were potential risks of liver dysfunction(61.0%) and kidney dysfunction(59.3%) associated with Suhexiang Pills.Conclusion:Experts generally believe that Suhexiang Pills are clinically suitable for the treatment of ischemic and hemorrhagic stroke patients who present with clinical manifestations such as clouding of consciousness,dizziness,vertigo,and phlegm-rattling in the throat caused by phlegm-dampness obstructing the orifices,and can be used in various clinical stages of stroke,mainly focusing on the acute phase.Suhexiang Pills are characterized by depleting qi with aromatics,so they should not be used for prolonged periods.Pregnancy and allergies are contraindications for Suhexiang Pills.Additionally,the liver and kidney toxicities caused by Cinnabaris should be carefully considered in clinical applications.

    参考文献
    相似文献
    引证文献
引用本文

熊雪娇,刘婷婷,秦明臻,赖新星,高颖.经典名方苏合香丸治疗中风临床精准定位研究的专家问卷调查[J].世界中医药,2023,(13).

复制
相关视频

分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:2023-05-10
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2023-08-01
  • 出版日期:
文章二维码