| 引用本文:蔡建辉1，李洪涛1，2，吴振华3，4，袁国栋4.输刺结合痹祺胶囊治疗神经根型颈椎病的临床疗效观察[J].世界中医药,2023,(13):. |
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| 输刺结合痹祺胶囊治疗神经根型颈椎病的临床疗效观察 |
| Clinical Efficacy of Transport Needling Combined with Biqi Capsules in the Treatment of Cervical Spondylopathy of Nerve Root Type |
| 投稿时间：2022-04-02 |
| DOI：10.3969/j.issn.1673-7202.2023.13.018 |
| 中文关键词: 神经根型 颈椎病 输刺 痹祺胶囊 颈椎功能障碍指数 视觉模拟评分法 疗效 临床观察 |
| English Keywords:Nerve root type Cervical spondylopathy Transport needling Biqi Capsules NDI VAS Efficacy Clinical observation |
| 基金项目:国家自然科学基金项目（82205314） |
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| 中文摘要: |
| 目的：观察输刺结合痹祺胶囊治疗神经根型颈椎病的临床疗效，为治疗神经根型颈椎病提供一种安全有效的治疗方法。方法：选取黑龙江中医药大学附属第一医院骨伤一科门诊就诊的神经根型颈椎病患者120例作为研究对象，随机分为观察组和对照组，每组60例。对照组采用常规西药的疗法，观察组在对照组基础上采用输刺结合痹祺胶囊疗法。比较2组患者治疗前后颈椎病临床评价量表（CASCS），颈椎功能障碍指数（NDI），Northwick Park颈痛量表（NPQ），视觉模拟评分法（VAS）。用酶联免疫吸附试验法测定血清白细胞介素-β（IL-β）、IL-6、肿瘤坏死因子-α（TNF-α）等炎症介质水平。结果：观察组总有效率93.33%（56/60），对照组总有效率75.00%（45/60），差异有统计学意义（P<0.05）。治疗后观察组CASCS、NDI、NPQ、VAS和炎症介质改善均较对照组明显，差异均有统计学意义（均P<0.05）。结论：输刺结合痹祺胶囊治疗神经根型颈椎病的临床疗效较好，可有效抑制炎症介质的释放和聚集，从而缓解颈肩部疼痛，改善功能障碍。 |
| English Summary: |
| To observe the clinical efficacy of transport needling combined with Biqi Capsules in treating cervical spondylopathy of nerve root type and provide a safe and effective treatment method for this disease.Methods:A total of 120 patients with cervical spondylopathy of nerve root type were randomly divided into an observation group and a control group，with 60 cases in each group.The control group received conventional western medicine treatment，while the observation group received the combined therapy of transport needling and Biqi Capsules in addition to the treatment received by the control group.The clinical evaluation scale for cervical spondylopathy(CASCS)，the neck disability index(NDI)，the Northwick Park neck pain questionnaire(NPQ)，and the visual analog scale(VAS) were compared before and after treatment between the two groups.Levels of inflammatory mediators such as interleukin(IL)-β，IL-6，and tumor necrosis factor(TNF)-α in the serum were determined by enzyme-linked immunosorbent assay.Results:The total effective rate was 93.33%(56/60) in the observation group and 75.00%(45/60) in the control group，with a statistically significant difference(P<0.05).After treatment，the improvement in CASCS，NDI，NPQ，VAS，and inflammatory mediators in the observation group was significantly better than that in the control group(all P<0.05).Conclusion:The combined therapy of transport needling and Biqu Capsules has good clinical efficacy in treating cervical spondylopathy，which can effectively inhibit the release and aggregation of inflammatory mediators，thereby relieving neck and shoulder pain and improving functional impairment. |
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