| 引用本文:岑园园1，郭义1，2，3，王平4，陈泽林1，2，3，陈波1，2，3，王军4，张云鹏4，曹率4，庄俊红4，李萌4，黄欣4，孙基峰4，汪益1.经皮穴位电刺激联合皮内针预防急性中重度放射性肺炎的临床研究[J].世界中医药,2023,(16):. |
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| 经皮穴位电刺激联合皮内针预防急性中重度放射性肺炎的临床研究 |
| Clinical Study of Transcutaneous Acupoint Electrical Stimulation Combined with Intradermal Needling in the Prevention and Treatment of Acute Moderate to Severe Radioactive Pneumonia |
| 投稿时间：2021-12-05 |
| DOI：10.3969/j.issn.1673-7202.2023.16.018 |
| 中文关键词: 针灸 经皮穴位电刺激 皮内针 放射性肺损伤 放射性肺炎 急性中重度放射性肺炎 临床研究 |
| English Keywords:Acupuncture Transcutaneous acupoint electrical stimulation Intradermal needling Radiation-induced lung injury Radioactive pneumonia Acute moderate to severe radioactive pneumonia Clinical research |
| 基金项目:国家重点研发计划中医药现代化研究重点专项项目（2019YFC1712200） |
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| 中文摘要: |
| 目的：观察经皮穴位电刺激(TEAS)联合皮内针（IN）对急性中重度急性放射性肺炎(AMTSRP)的预防作用。方法：选取２０２０年１１月至２０２１年１１月在天津市肿瘤医院空港医院放疗科门诊和住院部接受放射治疗的８４例肺癌患者作为研究对象，采用随机数字表法将受试者分为观察组和对照组，每组４２例。观察组采用TEAS联合IN进行治疗，1次/d，共30次。对照组不采用干预治疗。观察患者放疗1月后中AMTSRP的发生率、级别、中医临床症状评分、生命质量量表-C30（QLQ-C30）评分、QLQ-LC43评分、医院焦虑抑郁量表（HADS）评分、卡诺夫斯凯（KPS）评分、肿瘤患者体能状态（ZPS）评分及简明疲劳量表（BFI）评分。结果：观察组和对照组中AMTSRP的发生率分为7.5%和32.1%，差异有统计学意义（P<0.05）；除QLQ-LC43差异无统计学意义（P>0.05)外,其余评分差异都有统计学意义（P<0.05）。结论：TEAS联合IN可以降低肺癌患者AMTSRP的发生率和级别，减轻临床症状，提高生命质量，改善体能状态和疲劳情况，且能缓解心理焦虑和抑郁的情绪。 |
| English Summary: |
| This study aims to observe the effect of transcutaneous acupoint electrical stimulation(TEAS) combined with intradermal needling(IN) on the prevention of acute moderate to severe radioactive pneumonia(AMTSRP).Methods:A total of 84 patients with primary lung cancer who received radiotherapy were randomly divided into an acupoint treatment group and a control group，with 42 cases in each group.The acupoint treatment group was treated with TEAS combined with IN once a day for 30 times in total.The control group received no intervention.The incidence and grade of AMTSRP，TCM clinical symptom score，QLQ-C30 score，QLQ-LC43 score，HADS score，KPS score，ZPS score，and BFI score were observed one month after radiotherapy.Results:The incidence of AMTSRP in the acupoint treatment group and control group was 7.5% and 32.1%，with statistical differences(P<0.05).There was no statistical significance except QLQ-LC43(P>0.05)，and other scores were statistically significant(P<0.05).Conclusion:TEAS combined with IN can reduce the incidence and grade of AMTSRP in lung cancer patients，relieve clinical symptoms，enhance the quality of life，improve physical state and fatigue，and relieve psychological anxiety and depression. |
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