As a way of pro-inflammatory cell death，pyroptosis plays a role in the development of non-alcoholic steatohepatitis.The accumulation of phlegm，dampness and stasis in the liver is the core pathogenesis of non-alcoholic steatohepatitis，which may be associated with the pathogenesis of pyroptosis.Therefore，revealing the micro-connection of pyroptosis with phlegm，dampness and stasis to explore the mechanism of traditional Chinese medicine in the treatment of non-alcoholic steatohepatitis can provide new ideas for the treatment of this disease with integrated traditional Chinese and Western medicine.