| 引用本文:宋艺佳1，刘鸣昊2，赵文霞2.细胞焦亡与非酒精性脂肪性肝炎“痰湿瘀”病机的微观联系与治疗[J].世界中医药,2023,(17):. |
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| 细胞焦亡与非酒精性脂肪性肝炎“痰湿瘀”病机的微观联系与治疗 |
| Application of Pyroptosis in Treating Non-alcoholic Steatohepatitis Caused by Phlegm，Dampness and Stasis |
| 投稿时间：2022-01-06 |
| DOI：10.3969/j.issn.1673-7202.2023.17.012 |
| 中文关键词: 非酒精性脂肪性肝炎 痰湿瘀 细胞焦亡 中医 病机 微观联系 治疗 中药 微观辨证 |
| English Keywords:Non-alcoholic steatohepatitis Phlegm,Dampness and stasis Pyroptosis Traditional Chinese medicine Pathogenesis Micro connection Treatment Chinese medicines Micro syndrome differentiation |
| 基金项目:国家自然科学基金项目（81904154）;河南省科技攻关计划项目（202102310168） |
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| 中文摘要: |
| 细胞焦亡是一种促炎性细胞程序性死亡，在非酒精性脂肪性肝炎发展中扮演重要角色。“痰湿瘀”互结于肝络是非酒精性脂肪性肝炎的核心病机，与细胞焦亡之间可能存在一定的内在联系。因此，通过细胞焦亡与“痰湿瘀”病机的微观联系，探讨中药治疗非酒精性脂肪性肝炎的作用机制，为中药治疗非酒精性脂肪性肝炎的作用机制研究提供新思路。 |
| English Summary: |
| As a way of pro-inflammatory cell death，pyroptosis plays a role in the development of non-alcoholic steatohepatitis.The accumulation of phlegm，dampness and stasis in the liver is the core pathogenesis of non-alcoholic steatohepatitis，which may be associated with the pathogenesis of pyroptosis.Therefore，revealing the micro-connection of pyroptosis with phlegm，dampness and stasis to explore the mechanism of traditional Chinese medicine in the treatment of non-alcoholic steatohepatitis can provide new ideas for the treatment of this disease with integrated traditional Chinese and Western medicine. |
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