世界中医药
文章摘要
引用本文:阿依达娜·毛兰1,刘瑞2,花宝金2.基于“寒气生浊”理论探微癌性疼痛的机制与治疗[J].世界中医药,2023,(22):.  
基于“寒气生浊”理论探微癌性疼痛的机制与治疗
Mechanism and Treatment of Cancer Pain Based on the Theory of “Cold Qi Generates Turbidity”
投稿时间:2023-01-31  
DOI:10.3969/j.issn.1673-7202.2023.22.011
中文关键词:  癌性疼痛;扶正培本;寒气生浊;作用机制;治疗;肿瘤微环境;中医病机  中医外治法
English Keywords:Cancer pain  Reinforcing healthy qi and consolidating root  Theory of cold qi generates turbidity  Mechanism  Treatment  Cancer microenvironment  Pathogenesis of traditional Chinese medicine  External treatment of traditional Chinese medicine
基金项目:国家自然科学基金项目(82274609,82074338,82174465);国家中医药管理局中医药创新团队及人才支持计划项目(ZYYCXTD-C-202205);中国中医科学院科技创新工程项目(CI2021A01810,CI2021B009)
作者单位
阿依达娜·毛兰1,刘瑞2,花宝金2 1 北京中医药大学研究生院北京100029 2 中国中医科学院广安门医院肿瘤科北京100053 
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中文摘要:
      癌性疼痛为癌症中晚期患者最常见、最痛苦的症状之一,也是临床上待解决的难题之一。癌性疼痛发病机制复杂,目前仍沿用世界卫生组织颁布的三阶梯止痛方案,但治疗效果不理想。近年来,中西医结合治疗癌性疼痛的研究越来越广泛,且效果较佳。现基于《黄帝内经》中“寒气生浊”理论为核心,探微癌性疼痛微环境发病机制,提出整体以扶正培本为先,止痛以通阳调气为要,局部以通络化浊为主辨治癌性疼痛治疗思路,兼顾整体与局部治疗方案,为治疗癌性疼痛提供了可靠的理论依据和研究思路。
English Summary:
      Cancer pain is one of the most common and painful symptoms for patients with mid-to late-stage cancer,and it is also one clinical challenge to be solved.The pathogenesis of cancer pain is complex,and the three-step analgesic ladder promulgated by WHO is still being used,with unsatisfactory treatment effect.In recent years,studies on the treatment of cancer pain with integrative Chinese and western medicine have become wider and wider and shown desirable results.According to the theory of “cold qi generates turbidity” in Huangdi Neijing(Huangdi's Internal Classic),this paper explored the microenvironmental pathogenesis of cancer pain,and proposed the idea of syndrome differentiation and treatment.In other words,the overall treatment should be based on reinforcing healthy qi and cultivating root; the pain relief should be based on tonifying yang and regulating qi; the local treatment should be based on dredging collaterals and resolving turbidity.This idea involves simultaneous treatment of the whole body and the local area,which provides a reliable theoretical basis for the treatment of cancer pain.
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