To use data mining technology to explore clinical acupoint selection rules for menopausal insomnia.Methods:China National Knowledge Infrastructure(CNKI)，China Science Periodical Database(CSPD)，Chinese Citation Database(CCD)，China Biology Literature Medicine(CBM)，PubMed，Web of Science，Cochrane Library，andEmbased were searched from their establishment to November 2021，and the published literature on acupuncture treatment of menopausal insomnia was screened by inclusion and exclusion criteria，with a database of acupuncture prescriptions established.Excel was used to perform frequency statistical analysis on the obtained data，and SPSS molder was adopted to perform clustering and association rule analysis.Results:In acupuncture treatment of menopausal insomnia，the most frequantly used acupoints are Sanyinjiao(SP 6)，Baihui(GV 20)，Shenmen(HT 7)，Sishencong(EX-HN 1)，Shenshu(BL 23)，and Taixi(LR 3).The main meridians are the musculature bladder meridian and the governor channel.The acupoints are located in the lower limbs，followed by the head and neck.Among the specific acupoints，Jiaohui，Yuan，Wushu，and Beishu are more frequently used.Association rule analysis shows that Qihai(CV 6)-Guanyuan(CV 4)，Shenshu(CV 4)-Ganshu(BL 18)，and Xinshu(BL 15)-Shenshu(CV 4) are highly correlated.Cluster analysis of acupoints used more than six times results in seven cluster groups.Conclusion:Acupuncture is effective in treating menopausal insomnia.On the basis of disease differentiation and acupoint selection，more attention should be paid to regulating and supplementing the zang-fu organs and calming the mind and settling the mind，which fully embodies the medical characteristics of the overall concept of Traditional Chinese medicine.