To study the effect of purification on quality of Fructus Mume and perfect the quality standard of pulp of Fructus Mume.Methods:Firstly，three batches of Fructus Mume samples were prepared by steaming and moistening methods respectively.The differences between steaming method and moistening method in processing pulp of Fructus Mume were compared in terms of yield，extract and citric acid content to determine the purification method.According to the determined purification method，twelve batches of Fructus Mume were purified and the difference in contents of extract and citric acid between pulp and core of Fructus Mume were compared to explore the effect of purification on quality of Fructus Mume.The appearance，microstructure，thin-layer chromatography(TLC) identification，water content，water-soluble extract and citric acid content of twenty-one batches of pulp of Fructus Mume decoction pieces were determined according to the requirements of Chinese pharmacopoeia.The quality standard of pulp of Fructus Mume was formulated.Results:There was no significant difference in quality(yield，water content，citric acid content，extract content) between steaming method and moistening method.But the steaming method took 30 min，which was much shorter than that of the moistening method(overnight).The contents of extract and citric acid in pulp of Fructus Mume were 72.5% and 33.1%，respectively，which were much higher than those in the core of Fructus Mume(17.9% and 8.0%)，indicating that there were significant differences between the two purification methods.In pulp of Fructus Mume，the average water content was 11.0%±1.4%，the extract content was 72.0%±3.4%，and the citric acid content was 33.8%±4.5%.Conclusion:The purification methods of Fructus Mume can remove the non-medicinal parts，increase the content of citric acid and extract，which is scientifically reasonable.Both steaming and moistening methods are feasible，and steaming method is easier to operate.