| 引用本文:丁宁，张浩琳，辛喜艳，申洪波，李，赛叶，阳，李东.“润肺止咳方”干预新型冠状病毒感染后咳嗽的回顾性分析[J].世界中医药,2024,(03):. |
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| “润肺止咳方”干预新型冠状病毒感染后咳嗽的回顾性分析 |
| Review of Runfei Zhike Prescription Intervening Cough Following a COVID-19 Infection |
| 投稿时间：2023-08-24 |
| DOI：10.3969/j.issn.1673-7202.2024.03.016 |
| 中文关键词: 润肺止咳方 新型冠状病毒感染 中医药 咳嗽 临床疗效 回顾性分析 体质学说 |
| English Keywords:Runfei Zhike Prescription Corona Virus Disease 2019(COVID-19) infection Traditional Chinese medicine Cough Clinical efficacy Retrospective analysis Constitution theory |
| 基金项目:国家自然科学基金面上项目（82074193） |
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| 中文摘要: |
| 目的：评价2022年冬季北京大学第三医院“润肺止咳方”治疗新型冠状病毒感染后咳嗽患者的临床疗效。方法：回顾性收集2022年12月15日至2023年1月5日北京大学第三医院中医科门诊收治的新型冠状病毒感染后咳嗽患者108例，其中包括观察组68例和对照组40例。观察组给予“润肺止咳方”治疗，对照组对为未采用中医治疗的新型冠状病毒感染后咳嗽的临床患者，但可能有西医对症治疗。收集患者的基本资料、中医证候和用药情况，比较2组患者的体温复常时间、核酸转阴时间以及临床疗效。结果：与对照组比较，观察组的体温复常时间和核酸转阴时间差异无统计学意义（P=0.892，P=0.967）。观察组的临床治愈率为52.9%（36/68）、总有效率为88.2%（60/68），显著优于对照组的临床治愈率12.5%（5/40）、总有效率47.5%（19/40）（均P<0.01）。结论：北京大学第三医院“润肺止咳方”可改善新型冠状病毒感染患者的咳嗽症状，提高了中医治疗新型冠状病毒咳嗽后遗症的有效率和治愈率。 |
| English Summary: |
| To evaluate the clinical efficacy of Runfei Zhike Prescription from Peking University Third Hospital in the treatment of patients with cough following Corona Virus Disease 2019(COVID-19) infection.Methods:From December 15，2022 to January 5，2023，108 patients with cough following COVID-19 infection in the Department of Traditional Chinese Medicine，Peking University Third Hospital were retrospectively collected，including 68 cases in the observation group and 40 cases in the control group.The observation group was treated with Runfei Zhike Prescription，and the control group included patients with cough following COVID-19 infection who were not treated with any traditional Chinese medicine(TCM)，but there may be symptomatic treatment with Western medicine.The basic data，TCM syndromes，and medication of the patients were collected.The time of body temperature normalization，nucleic acid negative conversion，and clinical efficacy were compared between the two groups.Results:There was no statistical significance in the time of body temperature normalization and nucleic acid negative conversion between the two groups(P=0.892，P=0.967).The clinical cure rate and the total effective rate were 52.9%(36/68) and 88.2%(60/68) in the observation group，which were significantly better than the clinical cure rate of 12.5%(5/40) and the total effective rate of 47.5%(19/40) in the control group(P<0.01).Conclusion:Runfei Zhike Prescription from Peking University Third Hospital can improve the cough of patients following COVID-19 infection and enhance the effective rate and cure rate of TCM in treating cough following COVID-19 infection. |
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