This study aimed to systematically sort out and summarize the clinical prescriptions and characteristics of children with adenoid hypertrophy(AH)，and provided a reference for the selection of prescriptions and drugs for the treatment of this disease in traditional Chinese medicine.Methods:To search CNKI and CSPD from the establishment of the database to February 2022，all the clinical research literature on the treatment of children with adenoid hypertrophy by Chinese herbal medicines，this study built a database of Chinese medicines for the treatment of children with AH.The study used frequency statistical analysis of High-frequency traditional Chinese medicine and its efficacy and utilized IBM SPSS Modeler 18.0 to analyze the association rules of high-frequency drugs.It employed Cytoscape 3.9.1 to complete the visual construction of complex networks and finally used IBM SPSS Statistics 25.0 to conduct a systematic cluster analysis of high-frequency drugs.Results:The frequency of traditional Chinese medicine was Glycyrrhizae Radix et Rhizoma，Prunellae Spica，Magnoliae Flos，Xanthii Fructus，and Fritillariae Thunbergii Bulbus.The top three efficacy of high-frequency drugs were heat-clearing drugs，anti-surface drugs，and tonic drugs.In the association rule analysis，there were 5 drug-pair combinations with support>20% and 7 drug-pair combinations with confidence>90%.High-frequency drugs worked best when the intercept was 22 and the clustering was 5.Conclusion:Literature studies showed that the treatment of AH drugs in children was based on clearing fever，supplemented by qi supplementation，releasing exterior，blood activation and phlegm dissolving drugs to enhance the clinical efficacy.This study summarized the combination of Xiaoluo Pill，Liujunzi Decoction，Cangerzi Powder and Shengjiang Powder and other drug combinations，and extracted its previous medication characteristics as the same treatment of lungs and spleen and the same treatment of organs，providing a reference for clinical prescription medication.