| 引用本文:陆益平1，刘远洋1，叶嘉焕1，苏琳祺1，唐素梅1，傅鹏2，韦建华2，唐慧勤1,2.基于组分中药理论的薏苡仁-知母药对治疗糖尿病患者的配伍特点[J].世界中医药,2024,(09):. |
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| 基于组分中药理论的薏苡仁-知母药对治疗糖尿病患者的配伍特点 |
| Compatibility Characteristics of Coicis Semen-Anemarrhenae Rhizoma Drug Pair in the Treatment of Diabetes in Patients Based on the Theory of Chinese Medicine Components |
| 投稿时间：2022-10-26 |
| DOI：10.3969/j.issn.1673-7202.2024.09.020 |
| 中文关键词: 组分中药 薏苡仁 知母 药对 糖尿病 |
| English Keywords:Chinese medicine component Coicis Semen Anemarrhenae Rhizoma Drug pair Diabetes |
| 基金项目:国家重点研发计划项目(2019YFC1712304)；广西高校中青年教师基础能力提升项目(KY2016YB215)；中药学广西一流学科建设项目（桂教科研〔2022〕1号）；广西中医药大学项目（ZYX2017009、YSL17001、2021MS002、桂中医大科〔2022〕4号、桂中医大科〔2022〕3号）；广西壮瑶药重点实验室建设项目（桂科基字〔2014〕32号）；第八批广西壮族自治区特聘专家项目（桂人才通字〔2019〕13号）；广西研究生联合培养基地项目（桂学位〔2021〕6号） |
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| 中文摘要: |
| 药对是源于中医传统经方或验方，依据中药配伍原则，能长期应用并指导临床实践的两味药物相对固定的配伍形式，具有协同增效或配伍减毒的作用。薏苡仁-知母为典型的清热滋阴药对，二者相辅相成，治疗阴虚热盛型糖尿病患者效果显著。其成分知母皂苷、知母多糖、芒果苷、薏苡仁多糖等对糖尿病均有较好的干预作用。现从中医理论及现代药理学研究等层面探究薏苡仁-知母药对治疗糖尿病的配伍特点，剖析主要活性成分的降糖作用和作用机制，为治疗糖尿病的新药研究提供理论基础。 |
| English Summary: |
| Drug pair，originating from traditional Chinese medicine(TCM) classical formulas or empirical prescriptions，refers to a relatively fixed combination of two herbal drugs based on the principles of Chinese medicine compatibility.These combinations can be consistently applied and guide clinical practice，often enhancing efficacy or reducing toxicity through synergistic effects.Coicis Semen-Anemarrhenae Rhizoma is a typical drug pair known for its heat-clearing and yin-nourishing properties.They complement each other and have shown significant effectiveness in treating diabetes characterized by yin deficiency and exuberant heat.The active components，such as timosaponin，Anemarrhena asphodeloides polysaccharides，mangiferin，and coixanfrom，have demonstrated beneficial effects on diabetes.This paper explored the compatibility characteristics of Coicis Semen-Anemarrhenae Rhizoma drug pair in treating diabetes from both TCM theory and modern pharmacological research and analyzed the hypoglycemic effects and mechanisms of action of the main active components，providing a theoretical foundation for the new drug development for diabetes. |
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