| 引用本文:张敬于，安富竹，魏云霞，于旭峰，乔明琦.柴胡疏肝散治疗情志病的研究进展[J].世界中医药,2024,(09):. |
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| 柴胡疏肝散治疗情志病的研究进展 |
| Research Progress on Chaihu Shugan Powder in Treatment of Emotional Diseases |
| 投稿时间：2023-03-23 |
| DOI：10.3969/j.issn.1673-7202.2024.09.025 |
| 中文关键词: 柴胡疏肝散 情志病 抑郁症 围绝经期综合征 阿尔茨海默病 失眠 作用机制 研究进展 |
| English Keywords:Chaihu Shugan Powder Emotional diseases Depression Perimenopausal syndrome Alzheimer's disease Insomnia Mechanism of action Research Progress |
| 基金项目:国家科学技术部科技重大新药创制专项(2017ZX09301064)；山东省自然科学基金重点项目（ZR2020ZD17）；济南市“高校20条”资助项目（2020GXRC002） |
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| 中文摘要: |
| 情志病是指因情志刺激而致脏腑阴阳气血失调的一种疾病，可以概括为因情志刺激而发生的病证和因情志刺激而诱发的病证。情志病的发生与肝的特性和生理功能密切相关，肝主疏泄、肝主藏血是调节情志的重要基础，肝的疏泄失常、不能藏血是导致情志病发生的关键病机。柴胡疏肝散出自《景岳全书》，由柴胡、陈皮、川芎、枳壳、白芍、香附、炙甘草组成，主要功效为疏肝解郁、活血止痛。临床发现柴胡疏肝散可用于治疗抑郁症、阿尔茨海默病、睡眠障碍等精神障碍性疾病以及心理因素导致的围绝经期综合征、甲状腺疾病、乳腺增生等心身疾病，效果较好。本文对柴胡疏肝散治疗情志病的临床应用、作用机制进行综述，以期发挥中医药治疗情志病的优势，为中医药治疗情志病的临床工作提供支持。 |
| English Summary: |
| Emotional diseases refer to diseases caused by the imbalance of yin and yang，qi，and blood in the organs due to emotional stimuli.It can be summarized as both the occurrence and induction of diseases due to emotional stimuli.The occurrence of emotional diseases is closely related to the characteristics and physiological functions of the liver.The roles of liver in governing free flow of qi and storing blood are important foundations for regulating emotion.The key pathological mechanism leading to the occurrence of emotional diseases is the dysfunction of liver in governing free flow of qi and storing blood.Chaihu Shugan Powder，originating from Jing Yue's Collected Works(Jing Yue Quan Shu)，consists of Bupleuri Radix，Citri Reticulatae Pericarpium，Chuanxiong Rhizoma，Aurantii Fructus，Paeoniae Radix Alba，Cyperi Rhizoma，and Glycyrrhizae Radix et Rhizoma Praeparata cum Melle.Its main effects are soothing the liver，relieving depression，promoting blood circulation，and alleviating pain.Clinical observations have found that Chaihu Shugan Powder can be used to treat depression，Alzheimer's disease，sleep disorders，and other psychiatric disorders，as well as psychosomatic diseases such as premenstrual syndrome caused by psychological factors，thyroid diseases，and breast hyperplasia，with good efficacy.This article reviewed the clinical application and mechanism of action of Chaihu Shugan Powder in the treatment of emotional diseases，aiming to leverage the advantages of traditional Chinese medicine(TCM) in treating emotional diseases and provide support for the clinical work of TCM in treating emotional diseases. |
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